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SPTA1 Antikörper (AA 940-1160)

SPTA1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6148401
  • Target Alle SPTA1 Antikörper anzeigen
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Bindungsspezifität
    • 8
    • 1
    • 1
    • 1
    • 1
    AA 940-1160
    Reaktivität
    • 24
    • 12
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 17
    • 8
    Kaninchen
    Klonalität
    • 13
    • 12
    Polyklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTA1 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    KHEAFLLDLN SFGDSMKALR NQANACQQQQ AAPVEGVAGE QRVMALYDFQ ARSPREVTMK KGDVLTLLSS INKDWWKVEA ADHQGIVPAV YVRRLAHDEF PMLPQRRREE PGNITQRQEQ IENQYRSLLD RAEERRRRLL QRYNEFLLAY EAGDMLEWIQ EKKAENTGVE LDDVWELQKK FDEFQKDLNT NEPRLRDINK VADDLLFEGL LTPEGAQIRQ E
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human alpha 1 Spectrin (NP_003117.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Talhouarne, Gall: "7SL RNA in vertebrate red blood cells." in: RNA (New York, N.Y.), Vol. 24, Issue 7, pp. 908-914, (2018) (PubMed).

  • Target
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Andere Bezeichnung
    SPTA1 (SPTA1 Produkte)
    Synonyme
    Spna1 antikoerper, AF093576 antikoerper, AI451697 antikoerper, Spna-1 antikoerper, ha antikoerper, ihj antikoerper, nmf4 antikoerper, sph antikoerper, EL2 antikoerper, HPP antikoerper, HS3 antikoerper, SPH3 antikoerper, SPTA antikoerper, spectrin, alpha, erythrocytic 1 antikoerper, spectrin alpha, erythrocytic 1 antikoerper, Spta1 antikoerper, SPTA1 antikoerper
    Hintergrund
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.,SPTA1,EL2,HPP,HS3,SPH3,SPTA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Blood,Blood Cell Antigens,SPTA1
    Molekulargewicht
    279 kDa/280 kDa
    Gen-ID
    6708
    UniProt
    P02549
    Pathways
    Regulation of Actin Filament Polymerization
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