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SPAG8 Antikörper (AA 220-420)

SPAG8 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6148323
  • Target Alle SPAG8 Antikörper anzeigen
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-420
    Reaktivität
    • 47
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 44
    • 4
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPAG8 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 23
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    LVADRVPNYT SWSQHCPWEP QKQPPWEFLQ VLEPGARGLW KPPDIKGKLM VCYETLPRGQ CLLYNWEEER ATNHLDQVPS MQDGSESFFF RHGHRGLLTM QLKSPMPSST TQKDSYQPPG NVYWPLRGKR EAMLEMLLQH QICKEVQAEQ EPTRKLFEVE SVTHHDYRME LAQAGTPAPT KPHDYRQEQP ETFWIQRAPQ L
    Kreuzreaktivität
    Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human SPAG8 (NP_758516.1).
    Isotyp
    IgG
    Top Product
    Discover our top product SPAG8 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SPAG8 (Sperm Associated Antigen 8 (SPAG8))
    Andere Bezeichnung
    SPAG8 (SPAG8 Produkte)
    Synonyme
    BS-84 antikoerper, HSD-1 antikoerper, SMP1 antikoerper, SPAG3 antikoerper, hSMP-1 antikoerper, MH-SPAG8 antikoerper, sperm associated antigen 8 antikoerper, SPAG8 antikoerper, Spag8 antikoerper
    Hintergrund
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.,SPAG8,BS-84,CILD28,CT142,HSD-1,SMP1,SPAG3,hSMP-1,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Stem Cells,Germline Stem Cells,SPAG8
    Molekulargewicht
    44 kDa/51 kDa/53 kDa
    Gen-ID
    26206
    UniProt
    Q99932
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