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MTR4 Antikörper (AA 1-304)

SKIV2L2 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6147814
  • Target Alle MTR4 (SKIV2L2) Antikörper anzeigen
    MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
    Bindungsspezifität
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-304
    Reaktivität
    • 27
    • 15
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTR4 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Sequenz
    MADAFGDELF SVFEGDSTTA AGTKKDKEKD KGKWKGPPGS ADKAGKRFDG KLQSESTNNG KNKRDVDFEG TDEPIFGKKP RIEESITEDL SLADLMPRVK VQSVETVEGC THEVALPAEE DYLPLKPRVG KAAKEYPFIL DAFQREAIQC VDNNQSVLVS AHTSAGKTVC AEYAIALALR EKQRVIFTSP IKALSNQKYR EMYEEFQDVG LMTGDVTINP TASCLVMTTE ILRSMLYRGS EVMREVAWVI FDEIHYMRDS ERGVVWEETI ILLPDNVHYV FLSATIPNAR QFAEWICHLH KQPC
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MTR4 (SKIV2L2) (Superkiller Viralicidic Activity 2-Like 2 (SKIV2L2))
    Andere Bezeichnung
    SKIV2L2 (SKIV2L2 Produkte)
    Synonyme
    RGD1305984 antikoerper, zgc:63838 antikoerper, wu:fd11a05 antikoerper, SKIV2L2 antikoerper, skiv2l2 antikoerper, Dob1 antikoerper, KIAA0052 antikoerper, Mtr4 antikoerper, fSAP118 antikoerper, 2610528A15Rik antikoerper, mKIAA0052 antikoerper, Ski2 like RNA helicase 2 antikoerper, superkiller viralicidic activity 2-like 2 antikoerper, superkiller viralicidic activity 2-like 2 (S. cerevisiae) antikoerper, Skiv2l2 antikoerper, skiv2l2 antikoerper, SKIV2L2 antikoerper, LOC100380870 antikoerper
    Hintergrund
    Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT and poly(A tail exosome targeting (PAXT. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor ZCCHC8, which links to RNA-binding protein adapters. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. May be involved in pre-mRNA splicing. In the context of NEXT complex can also in vitro unwind DNA:RNA heteroduplexes with a 3' poly (A RNA tracking strand. Can promote unwinding and degradation of structured RNA substrates when associated with the nuclear exosome and its cofactors. Can displace a DNA strand while translocating on RNA to ultimately degrade the RNA within a DNA/RNA heteroduplex. Plays a role in DNA damage response.,SKIV2L2,Dob1,KIAA0052,Mtr4,fSAP118,Epigenetics & Nuclear Signaling,RNA Binding,SKIV2L2
    Molekulargewicht
    117 kDa
    Gen-ID
    23517
    UniProt
    P42285
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