SART1 Antikörper (AA 1-255)

Produktnummer ABIN6147390

Produktdetails anti-SART1 Antikörper

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Bindungsspezifität: AA 1-255

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SART1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Sequenz: MGSSKKHRGE KEAAGTTAAA GTGGATEQPP RHREHKKHKH RSGGSGGSGG ERRKRSRERG GERGSGRRGA EAEARSSTHG RERSQAEPSE RRVKREKRDD GYEAAASSKT SSGDASSLSI EETNKLRAKL GLKPLEVNAI KKEAGTKEEP VTADVINPMA LRQREELREK LAAAKEKRLL NQKLGKIKTL GEDDPWLDDT AAWIERSRQL QKEKDLAEKR AKLLEEMDQE FGVSTLVEEE FGQRRQDLYS ARDLQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human SART1 (NP_005137.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:20 - 1:50

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SART1

Target: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Andere Bezeichnung: SART1 (SART1 Produkte)

Synonyme: Dmel\\CG6686 antikoerper, SART1 antikoerper, MGC53679 antikoerper, MGC132129 antikoerper, zgc:91927 antikoerper, Ara1 antikoerper, HOMS1 antikoerper, SART1259 antikoerper, SNRNP110 antikoerper, Snu66 antikoerper, U5-110K antikoerper, CG6686 gene product from transcript CG6686-RB antikoerper, SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog antikoerper, SART1, U4/U6.U5 tri-snRNP-associated protein 1 antikoerper, squamous-cell carcinoma T-cell-recognized antigen antikoerper, squamous cell carcinoma antigen recognized by T cells 1 antikoerper, CG6686 antikoerper, sart1.S antikoerper, sart1 antikoerper, SART1 antikoerper, Sart1 antikoerper

Hintergrund: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.,SART1,Ara1,HOMS1,SART1259,SNRNP110,Snu66,HAF,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,SART1

Molekulargewicht: 90 kDa

Gen-ID: 9092

UniProt: O43290

Pathways: Ribonucleoprotein Complex Subunit Organization