RUNX1T1 Antikörper (AA 100-390)
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- Target Alle RUNX1T1 Antikörper anzeigen
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Bindungsspezifität
- AA 100-390
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RUNX1T1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GNDISPEIGE RVRTLVLGLV NSTLTIEEFH SKLQEATNFP LRPFVIPFLK ANLPLLQREL LHCARLAKQN PAQYLAQHEQ LLLDASTTSP VDSSELLLDV NENGKRRTPD RTKENGFDRE PLHSEHPSKR PCTISPGQRY SPNNGLSYQP NGLPHPTPPP PQHYRLDDMA IAHHYRDSYR HPSHRDLRDR NRPMGLHGTR QEEMIDHRLT DREWAEEWKH LDHLLNCIMD MVEKTRRSLT VLRRCQEADR EELNYWIRRY SDAEDLKKGG GSSSSHSRQQ SPVNPDPVAL D
- Kreuzreaktivität
- Human
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-390 of human RUNX1T1 (NP_783554.1).
- Isotyp
- IgG
- Top Product
- Discover our top product RUNX1T1 Primärantikörper
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- Applikationshinweise
- WB,1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Andere Bezeichnung
- RUNX1T1 (RUNX1T1 Produkte)
- Synonyme
- MTG8 antikoerper, si:ch211-232j17.1 antikoerper, wu:fi14b07 antikoerper, zgc:154044 antikoerper, AML1T1 antikoerper, CBFA2T1 antikoerper, CDR antikoerper, ETO antikoerper, ZMYND2 antikoerper, Cbfa2t1h antikoerper, Cbfa2t1 antikoerper, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antikoerper, RUNX1 translocation partner 1 L homeolog antikoerper, RUNX1 translocation partner 1 antikoerper, runx1t1 antikoerper, runx1t1.L antikoerper, RUNX1T1 antikoerper, Runx1t1 antikoerper
- Hintergrund
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.,RUNX1T1,AML1-MTG8,AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMYND2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,RUNX1T1
- Molekulargewicht
- 44 kDa/48 kDa/63 kDa/64 kDa/67 kDa/68 kDa
- Gen-ID
- 862
- UniProt
- Q06455
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