RGS14 Antikörper (AA 230-510)

Produktnummer ABIN6146917

Produktdetails anti-RGS14 Antikörper

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Bindungsspezifität: AA 230-510

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PPVEGPGGRP LRKSFRRELG GTANAALRRE SQGSLNSSAS LDLGFLAFVS SKSESHRKSL GSTEGESESR PGKYCCVYLP DGTASLALAR PGLTIRDMLA GICEKRGLSL PDIKVYLVGN EQALVLDQDC TVLADQEVRL ENRITFELEL TALERVVRIS AKPTKRLQEA LQPILEKHGL SPLEVVLHRP GEKQPLDLGK LVSSVAAQRL VLDTLPGVKI SKARDKSPCR SQGCPPRTQD KATHPPPASP SSLVKVPSSA TGKRQTCDIE GLVELLNRVQ S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-510 of human RGS14 (NP_006471.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Andere Bezeichnung: RGS14 (RGS14 Produkte)

Synonyme: RPIP1 antikoerper, MGC80558 antikoerper, RGS14 antikoerper, rgs14 antikoerper, wu:fi04g12 antikoerper, regulator of G protein signaling 14 antikoerper, regulator of G-protein signaling 14 antikoerper, regulator of G-protein signaling 14 L homeolog antikoerper, regulator of G-protein signalling 14 antikoerper, regulator of G protein signaling 14a antikoerper, RGS14 antikoerper, Rgs14 antikoerper, rgs14.L antikoerper, rgs14 antikoerper, rgs14a antikoerper

Hintergrund: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,RGS14,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),G2/M DNA Damage Checkpoint,RGS14

Molekulargewicht: 21 kDa/36 kDa/44 kDa/61 kDa

Gen-ID: 10636

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling