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PYCARD Antikörper (AA 50-195)

PYCARD Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6146515
  • Target Alle PYCARD Antikörper anzeigen
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Bindungsspezifität
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-195
    Reaktivität
    • 57
    • 10
    • 9
    • 1
    • 1
    • 1
    Human
    Wirt
    • 48
    • 7
    • 3
    Kaninchen
    Klonalität
    • 46
    • 12
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PYCARD Antikörper ist unkonjugiert
    Applikation
    • 40
    • 23
    • 14
    • 13
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    LDLTDKLVSF YLETYGAELT ANVLRDMGLQ EMAGQLQAAT HQGSGAAPAG IQAPPQSAAK PGLHFIDQHR AALIARVTNV EWLLDALYGK VLTDEQYQAV RAEPTNPSKM RKLFSFTPAW NWTCKDLLLQ ALRESQSYLV EDLERS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 50-195 of human ASC / TMS1 (NP_037390.2).
    Isotyp
    IgG
    Top Product
    Discover our top product PYCARD Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Gong, Chen, Xiong, Zhou, Huang, Kong: "NLRP3 inflammasome sequential changes in Staphylococcus aureus-induced mouse model of acute rhinosinusitis." in: International journal of molecular sciences, Vol. 15, Issue 9, pp. 15806-20, (2015) (PubMed).

  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Andere Bezeichnung
    PYCARD (PYCARD Produkte)
    Synonyme
    ASC antikoerper, CARD5 antikoerper, TMS antikoerper, TMS-1 antikoerper, TMS1 antikoerper, 9130417A21Rik antikoerper, Asc antikoerper, TNS1 antikoerper, masc antikoerper, asc1 antikoerper, zAsc antikoerper, zgc:109874 antikoerper, PYD and CARD domain containing antikoerper, PYCARD antikoerper, Pycard antikoerper, pycard antikoerper
    Hintergrund
    This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.,PYCARD,ASC,CARD5,TMS,TMS-1,TMS1,PYD and CARD domain containing,ASC / TMS1,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Apoptosis,Caspases,PYCARD
    Molekulargewicht
    15 kDa/19 kDa/21 kDa
    Gen-ID
    29108
    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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