PSMD12 Antikörper (AA 197-456)

Produktnummer ABIN6146334

Produktdetails anti-PSMD12 Antikörper

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Bindungsspezifität: AA 197-456

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KDYIRTQIIS KKINTKFFQE ENTEKLKLKY YNLMIQLDQH EGSYLSICKH YRAIYDTPCI QAESEKWQQA LKSVVLYVIL APFDNEQSDL VHRISGDKKL EEIPKYKDLL KLFTTMELMR WSTLVEDYGM ELRKGSLESP ATDVFGSTEE GEKRWKDLKN RVVEHNIRIM AKYYTRITMK RMAQLLDLSV DESEAFLSNL VVNKTIFAKV DRLAGIINFQ RPKDPNNLLN DWSQKLNSLM SLVNKTTHLI AKEEMIHNLQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 197-456 of human PSMD12 (NP_002807.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PSMD12

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Andere Bezeichnung: PSMD12 (PSMD12 Produkte)

Synonyme: wu:fb38a06 antikoerper, wu:fc34f08 antikoerper, wu:fc49f02 antikoerper, PSMD12 antikoerper, rpn5 antikoerper, Rpn5 antikoerper, p55 antikoerper, 1500002F15Rik antikoerper, AI480719 antikoerper, P55 antikoerper, proteasome 26S subunit, non-ATPase 12 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antikoerper, psmd12 antikoerper, PSMD12 antikoerper, Psmd12 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PSMD12,Rpn5,p55,STISS,Cell Biology & Developmental Biology,Ubiquitin,PSMD12

Molekulargewicht: 50 kDa/52 kDa

Gen-ID: 5718

UniProt: O00232

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway