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PRKAB1 Antikörper (AA 1-80)

PRKAB1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6146174
  • Target Alle PRKAB1 Antikörper anzeigen
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    Bindungsspezifität
    • 20
    • 17
    • 15
    • 15
    • 15
    • 13
    • 10
    • 9
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-80
    Reaktivität
    • 120
    • 100
    • 97
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 142
    • 9
    Kaninchen
    Klonalität
    • 133
    • 18
    Polyklonal
    Konjugat
    • 52
    • 10
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    Dieser PRKAB1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 65
    • 65
    • 53
    • 34
    • 22
    • 15
    • 15
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    MGNTSSERAA LERHGGHKTP RRDSSGGTKD GDRPKILMDS PEDADLFHSE EIKAPEKEEF LAWQHDLEVN DKAPAQARPT
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human AMPKbeta1 (NP_006244.2).
    Isotyp
    IgG
    Top Product
    Discover our top product PRKAB1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    Andere Bezeichnung
    PRKAB1 (PRKAB1 Produkte)
    Synonyme
    AMPK antikoerper, HAMPKb antikoerper, 1300015D22Rik antikoerper, AU021155 antikoerper, E430008F22 antikoerper, MGC82489 antikoerper, prkab1 antikoerper, wu:fk93d05 antikoerper, wu:fw87e09 antikoerper, zgc:56652 antikoerper, zgc:76975 antikoerper, zgc:92228 antikoerper, protein kinase AMP-activated non-catalytic subunit beta 1 antikoerper, protein kinase, AMP-activated, beta 1 non-catalytic subunit antikoerper, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antikoerper, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antikoerper, PRKAB1 antikoerper, Prkab1 antikoerper, prkab1.S antikoerper, prkab1 antikoerper, prkab1b antikoerper, prkab1a antikoerper
    Hintergrund
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.,PRKAB1,AMPK,HAMPKb,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Cardiovascular,Lipids,Fatty Acids,Regulator of mTOR complex function,Regulators,PRKAB1
    Molekulargewicht
    30 kDa
    Gen-ID
    5564
    UniProt
    Q9Y478
    Pathways
    AMPK Signaling, Warburg Effekt
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