PLOD2 Antikörper (AA 470-650)

Produktnummer ABIN6145788

Produktdetails anti-PLOD2 Antikörper

Target: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Bindungsspezifität: AA 470-650

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLOD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KTLRSEMNER NYFVRDKLDP DMALCRNARE MTLQREKDSP TPETFQMLSP PKGVFMYISN RHEFGRLLST ANYNTSHYNN DLWQIFENPV DWKEKYINRD YSKIFTENIV EQPCPDVFWF PIFSEKACDE LVEEMEHYGK WSGGKHHDSR ISGGYENVPT DDIHMKQVDL ENVWLHFIRE F

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-650 of human PLOD2 (NP_891988.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PLOD2

Target: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Andere Bezeichnung: PLOD2 (PLOD2 Produkte)

Synonyme: D530025C14Rik antikoerper, LH2 antikoerper, Plod-2 antikoerper, TLH antikoerper, procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 antikoerper, procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 antikoerper, Plod2 antikoerper, PLOD2 antikoerper

Hintergrund: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.,PLOD2,BRKS2,LH2,TLH,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,PLOD2

Molekulargewicht: 49 kDa/84 kDa/87 kDa

Gen-ID: 5352

UniProt: O00469

Pathways: SARS-CoV-2 Protein Interaktom