PAK4 Antikörper (AA 120-280)

Produktnummer ABIN6145188

Produktdetails anti-PAK4 Antikörper

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Bindungsspezifität: AA 120-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: EPATTARGGP GKAGSRGRFA GHSEAGGGSG DRRRAGPEKR PKSSREGSGG PQESSRDKRP LSGPDVGTPQ PAGLASGAKL AAGRPFNTYP RADTDHPSRG AQGEPHDVAP NGPSAGGLAI PQSSSSSSRP PTRARGAPSP GVLGPHASEP QLAPPACTPA A

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human PAK4 (NP_001014831.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Andere Bezeichnung: PAK4 (PAK4 Produkte)

Synonyme: 5730488L07Rik antikoerper, AW555722 antikoerper, mKIAA1142 antikoerper, im:5916170 antikoerper, wu:fd12b01 antikoerper, zgc:92014 antikoerper, p21 (RAC1) activated kinase 4 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 4 antikoerper, PAK4 antikoerper, Pak4 antikoerper, pak4 antikoerper

Hintergrund: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,PAK4,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cytoskeleton,Microfilaments,TGF-b-Smad Signaling Pathway,PAK4

Molekulargewicht: 47 kDa/48 kDa/54 kDa/64 kDa

Gen-ID: 10298

UniProt: O96013

Pathways: RTK Signalweg