PADI1 Antikörper (AA 1-260)

Produktnummer ABIN6145161

Produktdetails anti-PADI1 Antikörper

Target: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Bindungsspezifität: AA 1-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PADI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAPKRVVQLS LKMPTHAVCV VGVEAHVDIH SDVPKGANSF RVSGSSGVEV FMVYNRTRVK EPIGKARWPL DTDADMVVSV GTASKELKDF KVRVSYFGEQ EDQALGRSVL YLTGVDISLE VDTGRTGKVK RSQGDKKTWR WGPEGYGAIL LVNCDRDNHR SAEPDLTHSW LMSLADLQDM SPMLLSCNGP DKLFDSHKLV LNVPFSDSKR VRVFCARGGN SLSDYKQVLG PQCLSYEVER QPGEQEIKFY VEGLTFPDAD

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PADI1 (NP_037490.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PADI1

Target: PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))

Andere Bezeichnung: PADI1 (PADI1 Produkte)

Hintergrund: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.,PADI1,HPAD10,PAD1,PDI,PDI1,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PADI1

Molekulargewicht: 74 kDa

Gen-ID: 29943

UniProt: Q9ULC6