PACS1 Antikörper (AA 420-560)

Produktnummer ABIN6145155

Produktdetails anti-PACS1 Antikörper

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Bindungsspezifität: AA 420-560

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SKGSLGKDTT SPMELAALEK IKSTWIKNQD DSLTETDTLE ITDQDMFGDA STSLVVPEKV KTPMKSSKTD LQGSASPSKV EGVHTPRQKR STPLKERQLS KPLSERTNSS DSERSPDLGH STQIPRKVVY DQLNQILVSD A

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 420-560 of human PACS1 (NP_060496.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Andere Bezeichnung: PACS1 (PACS1 Produkte)

Synonyme: MRD17 antikoerper, AI325977 antikoerper, Pacs-1 antikoerper, phosphofurin acidic cluster sorting protein 1 antikoerper, PACS1 antikoerper, Pacs1 antikoerper

Hintergrund: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.,PACS1,MRD17,SHMS,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,PACS1

Molekulargewicht: 104 kDa/109 kDa

Gen-ID: 55690

UniProt: Q6VY07