PABPC4 Antikörper (AA 350-450)

Produktnummer ABIN6145149

Produktdetails anti-PABPC4 Antikörper

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Bindungsspezifität: AA 350-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PABPC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: VTEMNGRIVG SKPLYVALAQ RKEERKAHLT NQYMQRVAGM RALPANAILN QFQPAAGGYF VPAVPQAQGR PPYYTPNQLA QMRPNPRWQQ GGRPQGFQGM P

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC4 (NP_003810.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PABPC4

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Andere Bezeichnung: PABPC4 (PABPC4 Produkte)

Synonyme: cb12 antikoerper, sb:cb12 antikoerper, PABP antikoerper, ePAB antikoerper, ePABP antikoerper, APP-1 antikoerper, APP1 antikoerper, PABP4 antikoerper, iPABP antikoerper, polyadenylate-binding protein 4 antikoerper, poly(A) binding protein, cytoplasmic 4 antikoerper, poly(A) binding protein, cytoplasmic 4 (inducible form) antikoerper, poly(A) binding protein cytoplasmic 4 L homeolog antikoerper, poly(A) binding protein cytoplasmic 4 antikoerper, Bm1_06880 antikoerper, Pabpc4 antikoerper, pabpc4 antikoerper, pabpc4.L antikoerper, PABPC4 antikoerper

Hintergrund: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PABPC4,APP-1,APP1,PABP4,iPABP,Epigenetics & Nuclear Signaling,RNA Binding,PABPC4

Molekulargewicht: 69 kDa/70 kDa/72 kDa

Gen-ID: 8761

UniProt: Q13310

Pathways: SARS-CoV-2 Protein Interaktom