METTL13 Antikörper (AA 430-699)

Produktnummer ABIN6143755

Produktdetails anti-METTL13 Antikörper

Target: METTL13 (Methyltransferase Like 13 (METTL13))

Bindungsspezifität: AA 430-699

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: LKDVSHKAQK KRKKDRKKQR PADAEDLPAA PGQSIDKSYL CCEHHKAMIA GLALLRNPEL LLEIPLALLV VGLGGGSLPL FVHDHFPKSC IDAVEIDPSM LEVATQWFGF SQSDRMKVHI ADGLDYIASL AGGGEARPCY DVIMFDVDSK DPTLGMSCPP PAFVEQSFLQ KVKSILTPEG VFILNLVCRD LGLKDSVLAG LKAVFPLLYV RRIEGEVNEI LFCQLHPEQK LATPELLETA QALERTLRKP GRGWDDTYVL SDMLKTVKIV

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-699 of human METTL13 (NP_057019.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu METTL13

Target: METTL13 (Methyltransferase Like 13 (METTL13))

Andere Bezeichnung: METTL13 (METTL13 Produkte)

Synonyme: METTL13 antikoerper, KIAA0859 antikoerper, cgi-01 antikoerper, kiaa0859 antikoerper, RGD1311526 antikoerper, 5630401D24Rik antikoerper, feat antikoerper, si:dkey-19f21.2 antikoerper, zgc:152769 antikoerper, methyltransferase like 13 antikoerper, methyltransferase like 13 S homeolog antikoerper, METTL13 antikoerper, mettl13 antikoerper, Mettl13 antikoerper, mettl13.S antikoerper

Hintergrund: Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.,METTL13,5630401D24Rik,CGI-01,KIAA0859,feat,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,METTL13

Molekulargewicht: 44 kDa/61 kDa/68 kDa/72 kDa/78 kDa

Gen-ID: 51603

UniProt: Q8N6R0