MAN2B1 Antikörper (AA 640-850)

Produktnummer ABIN6143456

Produktdetails anti-MAN2B1 Antikörper

Target: MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))

Bindungsspezifität: AA 640-850

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAN2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TFFWYNASIG DNESDQASGA YIFRPNQQKP LPVSRWAQIH LVKTPLVQEV HQNFSAWCSQ VVRLYPGQRH LELEWSVGPI PVGDTWGKEV ISRFDTPLET KGRFYTDSNG REILERRRDY RPTWKLNQTE PVAGNYYPVN TRIYITDGNM QLTVLTDRSQ GGSSLRDGSL ELMVHRRLLK DDGRGVSEPL MENGSGAWVR GRHLVLLDTA Q

Kreuzreaktivität: Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 640-850 of human MAN2B1 (NP_000519.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAN2B1

Target: MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1))

Andere Bezeichnung: MAN2B1 (MAN2B1 Produkte)

Synonyme: AW107687 antikoerper, LAMAN antikoerper, Laman antikoerper, Manb antikoerper, MANB antikoerper, mannosidase alpha class 2B member 1 antikoerper, mannosidase, alpha, class 2B, member 1 antikoerper, mannosidase 2, alpha B1 antikoerper, MAN2B1 antikoerper, man2b1 antikoerper, Man2b1 antikoerper

Hintergrund: This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MAN2B1,LAMAN,MANB,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,MAN2B1

Molekulargewicht: 113 kDa

Gen-ID: 4125

UniProt: O00754