KPNA6 Antikörper (AA 277-536)

Produktnummer ABIN6142995

Produktdetails anti-KPNA6 Antikörper

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Bindungsspezifität: AA 277-536

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SYLSDGPNEK IQAVIDSGVC RRLVELLMHN DYKVASPALR AVGNIVTGDD IQTQVILNCS ALPCLLHLLS SPKESIRKEA CWTISNITAG NRAQIQAVID ANIFPVLIEI LQKAEFRTRK EAAWAITNAT SGGTPEQIRY LVSLGCIKPL CDLLTVMDSK IVQVALNGLE NILRLGEQEG KRSGSGVNPY CGLIEEAYGL DKIEFLQSHE NQEIYQKAFD LIEHYFGVED DDSSLAPQVD ETQQQFIFQQ PEAPMEGFQL

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 277-536 of human KPNA6 (NP_036448.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KPNA6

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Andere Bezeichnung: KPNA6 (KPNA6 Produkte)

Synonyme: IPOA7 antikoerper, Kpna5 antikoerper, NPI-2 antikoerper, KPNA7 antikoerper, karyopherin subunit alpha 6 antikoerper, karyopherin (importin) alpha 6 antikoerper, karyopherin alpha 6 (importin alpha 7) antikoerper, karyopherin alpha 6 (importin alpha 7) S homeolog antikoerper, KPNA6 antikoerper, Kpna6 antikoerper, kpna6.S antikoerper

Hintergrund: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.,KPNA6,IPOA7,KPNA7,Signal Transduction,KPNA6

Molekulargewicht: 60 kDa

Gen-ID: 23633

UniProt: O60684

Pathways: Protein targeting to Nucleus