IL17RA Antikörper (AA 697-866)

Produktnummer ABIN6142322

Produktdetails anti-IL17RA Antikörper

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Bindungsspezifität: AA 697-866

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGEGEACPLL GSPGAGRNSV LFLPVDPEDS PLGSSTPMAS PDLLPEDVRE HLEGLMLSLF EQSLSCQAQG GCSRPAMVLT DPHTPYEEEQ RQSVQSDQGY ISRSSPQPPE GLTEMEEEEE EEQDPGKPAL PLSPEDLESL RSLQRQLLFR QLQKNSGWDT MGSESEGPSA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 697-866 of human IL17RA (NP_055154.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-IL17RA Antikörper (ABIN6142322)

Ganesan, Rasool: "Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like synoviocytes in rheumatoid arthritis." in: Molecular immunology, Vol. 91, pp. 134-144, (2017) (PubMed).

Details zu IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Andere Bezeichnung: IL17RA (IL17RA Produkte)

Synonyme: IL17R antikoerper, CANDF5 antikoerper, CD217 antikoerper, CDw217 antikoerper, IL-17RA antikoerper, hIL-17R antikoerper, Il17r antikoerper, AW538159 antikoerper, Cdw217 antikoerper, VDw217 antikoerper, interleukin 17 receptor A antikoerper, IL17RA antikoerper, Il17ra antikoerper

Hintergrund: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.,IL17RA,CANDF5,CD217,CDw217,IL-17RA,IL17R,IMD51,hIL-17R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL17RA

Molekulargewicht: 92 kDa/96 kDa

Gen-ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interaktom