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IFI27 Antikörper (AA 1-100)

IFI27 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6142164
  • Target Alle IFI27 Antikörper anzeigen
    IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 32
    • 6
    • 2
    • 2
    • 1
    Human
    Wirt
    • 30
    • 2
    Kaninchen
    Klonalität
    • 31
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IFI27 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 13
    • 13
    • 12
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequenz
    MEASALTSSA VTSVAKVVRV ASGSAVVLPL ARIATVVIGG VVAVPMVLSA MGFTAAGIAS SSIAAKMMSA AAIANGGGVA SGSLVATLQS LGATGLSGLT
    Kreuzreaktivität
    Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IFI27 (Interferon, alpha-Inducible Protein 27 (IFI27))
    Andere Bezeichnung
    IFI27 (IFI27 Produkte)
    Synonyme
    FAM14D antikoerper, ISG12 antikoerper, ISG12A antikoerper, P27 antikoerper, IRG1 antikoerper, Ifi27l antikoerper, Ifi27l1 antikoerper, isg12(a) antikoerper, interferon alpha inducible protein 27 antikoerper, interferon, alpha-inducible protein 27 antikoerper, IFI27 antikoerper, Ifi27 antikoerper
    Hintergrund
    Probable adapter protein involved in different biological processes. Part of the signaling pathways that lead to apoptosis. Involved in type-I interferon-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Also functions in TNFSF10-induced apoptosis. May also have a function in the nucleus, where it may be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors. May thereby play a role in the vascular response to injury (By similarity. In the innate immune response, has an antiviral activity towards hepatitis C virus/HCV. May prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A and the ubiquitination machinery via SKP2, promoting the ubiquitin-mediated proteasomal degradation of NS5A.,IFI27,FAM14D,ISG12,ISG12A,P27,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,IFI27
    Molekulargewicht
    11 kDa
    Gen-ID
    3429
    UniProt
    P40305
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagie
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