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Granulin Antikörper (AA 281-336)

GRN Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6141431
  • Target Alle Granulin (GRN) Antikörper anzeigen
    Granulin (GRN)
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-336
    Reaktivität
    • 51
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 9
    • 5
    • 2
    • 1
    Kaninchen
    Klonalität
    • 48
    • 11
    Polyklonal
    Konjugat
    • 35
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Granulin Antikörper ist unkonjugiert
    Applikation
    • 52
    • 19
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    DVKCDMEVSC PDGYTCCRLQ SGAWGCCPFT QAVCCEDHIH CCPAGFTCDT QKGTCE
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 281-336 of human Granulin (NP_002078.1).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Granulin (GRN)
    Andere Bezeichnung
    GRN (GRN Produkte)
    Synonyme
    GRN antikoerper, grn antikoerper, wu:fb11g12 antikoerper, wu:fj18f05 antikoerper, MGC53354 antikoerper, DKFZp459H066 antikoerper, CLN11 antikoerper, GEP antikoerper, GP88 antikoerper, PCDGF antikoerper, PEPI antikoerper, PGRN antikoerper, epithelin antikoerper, acrogranin antikoerper, granulin precursor antikoerper, granulin a antikoerper, Granulins antikoerper, granulin L homeolog antikoerper, granulin antikoerper, GRN antikoerper, grna antikoerper, grn antikoerper, grn.L antikoerper, granulin antikoerper, ORF1 granulin antikoerper, Grn antikoerper
    Hintergrund
    Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.,GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN,granulins,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Neurodegenerative Diseases,GRN
    Molekulargewicht
    44 kDa/46 kDa/63 kDa
    Gen-ID
    2896
    UniProt
    P28799
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