GIPR Antikörper (AA 22-138)
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- Target Alle GIPR Antikörper anzeigen
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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Bindungsspezifität
- AA 22-138
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GIPR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- RAETGSKGQT AGELYQRWER YRRECQETLA AAEPPSGLAC NGSFDMYVCW DYAAPNATAR ASCPWYLPWH HHVAAGFVLR QCGSDGQWGL WRDHTQCENP EKNEAFLDQR LILERLQ
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1).
- Isotyp
- IgG
- Top Product
- Discover our top product GIPR Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).
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Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).
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- Target
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Andere Bezeichnung
- GIPR (GIPR Produkte)
- Synonyme
- GIPR antikoerper, PGQTL2 antikoerper, GIP-R antikoerper, Gm1081 antikoerper, Gm160 antikoerper, Gippr antikoerper, RATGIPPR antikoerper, gastric inhibitory polypeptide receptor antikoerper, glucagon receptor antikoerper, GIPR antikoerper, LOC100303705 antikoerper, Gipr antikoerper
- Hintergrund
- This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.,GIPR,PGQTL2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GIPR
- Molekulargewicht
- 48 kDa/49 kDa/53 kDa
- Gen-ID
- 2696
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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