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GIPR Antikörper (AA 22-138)

GIPR Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6141096
  • Target Alle GIPR Antikörper anzeigen
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    Bindungsspezifität
    • 10
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-138
    Reaktivität
    • 60
    • 26
    • 24
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 60
    • 1
    Kaninchen
    Klonalität
    • 61
    Polyklonal
    Konjugat
    • 32
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GIPR Antikörper ist unkonjugiert
    Applikation
    • 52
    • 24
    • 11
    • 10
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    RAETGSKGQT AGELYQRWER YRRECQETLA AAEPPSGLAC NGSFDMYVCW DYAAPNATAR ASCPWYLPWH HHVAAGFVLR QCGSDGQWGL WRDHTQCENP EKNEAFLDQR LILERLQ
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 22-138 of human GIPR (NP_000155.1).
    Isotyp
    IgG
    Top Product
    Discover our top product GIPR Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ussher, Campbell, Mulvihill, Baggio, Bates, McLean, Gopal, Capozzi, Yusta, Cao, Ali, Kim, Kabir, Seino, Suzuki, Drucker: "Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction." in: Cell metabolism, Vol. 27, Issue 2, pp. 450-460.e6, (2018) (PubMed).

  • Target
    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
    Andere Bezeichnung
    GIPR (GIPR Produkte)
    Synonyme
    GIPR antikoerper, PGQTL2 antikoerper, GIP-R antikoerper, Gm1081 antikoerper, Gm160 antikoerper, Gippr antikoerper, RATGIPPR antikoerper, gastric inhibitory polypeptide receptor antikoerper, glucagon receptor antikoerper, GIPR antikoerper, LOC100303705 antikoerper, Gipr antikoerper
    Hintergrund
    This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.,GIPR,PGQTL2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GIPR
    Molekulargewicht
    48 kDa/49 kDa/53 kDa
    Gen-ID
    2696
    UniProt
    P48546
    Pathways
    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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