FLT4 Antikörper (AA 1174-1363)

Produktnummer ABIN6140699

Produktdetails anti-FLT4 Antikörper

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Bindungsspezifität: AA 1174-1363

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLT4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: QGRGLQEEEE VCMAPRSSQS SEEGSFSQVS TMALHIAQAD AEDSPPSLQR HSLAARYYNW VSFPGCLARG AETRGSSRMK TFEEFPMTPT TYKGSVDNQT DSGMVLASEE FEQIESRHRQ ESGFSCKGPG QNVAVTRAHP DSQGRRRRPE RGARGGQVFY NSEYGELSEP SEEDHCSPSA RVTFFTDNSY

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1174-1363 of human FLT4 (NP_891555.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FLT4 Antikörper (ABIN6140699)

Yang, Sun, He, Ren, Liu, Liu, Zhang, Zhao: "Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation." in: The American journal of pathology, Vol. 187, Issue 11, pp. 2602-2615, (2017) (PubMed).

Details zu FLT4

Target: FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

Andere Bezeichnung: FLT4 (FLT4 Produkte)

Hintergrund: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.,FLT4,FLT-4,FLT41,LMPH1A,PCL,VEGFR-3,VEGFR3,Epigenetics & Nuclear Signaling,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,VEGF,VEGF Receptors,Cardiovascular,Angiogenesis,Angiogenic growth factors,FLT4

Molekulargewicht: 93 kDa/145 kDa/152 kDa

Gen-ID: 2324

UniProt: P35916

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling