EP400 Antikörper (AA 90-330)

Produktnummer ABIN6140195

Produktdetails anti-EP400 Antikörper

Target: EP400 (E1A Binding Protein P400 (EP400))

Bindungsspezifität: AA 90-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EP400 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLAPLPLPSP TSPGFQFSAQ PRRFEHGSPS YIQVTSPLSQ QVQTQSPTQP SPGPGQALQN VRAGAPGPGL GLCSSSPTGG FVDASVLVRQ ISLSPSSGGH FVFQDGSGLT QIAQGAQVQL QHPGTPITVR ERRPSQPHTQ SGGTIHHLGP QSPAAAGGAG LQPLASPSHI TTANLPPQIS SIIQGQLVQQ QQVLQGPPLP RPLGFERTPG VLLPGAGGAA GFGMTSPPPP TSPSRTAVPP G

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-330 of human EP400 (NP_056224.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EP400

Target: EP400 (E1A Binding Protein P400 (EP400))

Andere Bezeichnung: EP400 (EP400 Produkte)

Synonyme: CAGH32 antikoerper, P400 antikoerper, TNRC12 antikoerper, 1700020J09Rik antikoerper, AU023439 antikoerper, mDomino antikoerper, mKIAA1498 antikoerper, p400 antikoerper, E1A binding protein p400 antikoerper, EP400 N-terminal-like protein antikoerper, helicase domino antikoerper, E1a binding protein P400 antikoerper, EP400 antikoerper, Ep400 antikoerper, LOC738562 antikoerper, LOC5570719 antikoerper, CpipJ_CPIJ007689 antikoerper, CpipJ_CPIJ007688 antikoerper, CpipJ_CPIJ007686 antikoerper, CpipJ_CPIJ008061 antikoerper

Hintergrund: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.,EP400,CAGH32,P400,TNRC12,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EP400

Molekulargewicht: 331 kDa/335 kDa/339 kDa/343 kDa

Gen-ID: 57634

UniProt: Q96L91

Pathways: Chromatin Binding