Seladin 1 Antikörper (AA 227-516)

Produktnummer ABIN6139576

Produktdetails anti-Seladin 1 Antikörper

Target: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Bindungsspezifität: AA 227-516

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Seladin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AEIRIIPAKK YVKLRFEPVR GLEAICAKFT HESQRQENHF VEGLLYSLDE AVIMTGVMTD EAEPSKLNSI GNYYKPWFFK HVENYLKTNR EGLEYIPLRH YYHRHTRSIF WELQDIIPFG NNPIFRYLFG WMVPPKISLL KLTQGETLRK LYEQHHVVQD MLVPMKCLQQ ALHTFQNDIH VYPIWLCPFI LPSQPGLVHP KGNEAELYID IGAYGEPRVK HFEARSCMRQ LEKFVRSVHG FQMLYADCYM NREEFWEMFD GSLYHKLREK LGCQDAFPEV YDKICKAARH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 227-516 of human DHCR24 (NP_055577.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Seladin 1

Target: Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))

Andere Bezeichnung: DHCR24 (DHCR24 Produkte)

Synonyme: MGC82737 antikoerper, zgc:101638 antikoerper, DCE antikoerper, Nbla03646 antikoerper, SELADIN1 antikoerper, seladin-1 antikoerper, 2310076D10Rik antikoerper, 5830417J06Rik antikoerper, mKIAA0018 antikoerper, 24-dehydrocholesterol reductase antikoerper, 24-dehydrocholesterol reductase S homeolog antikoerper, delta(24)-sterol reductase antikoerper, DHCR24 antikoerper, dhcr24.S antikoerper, dhcr24 antikoerper, LOC5575872 antikoerper, CpipJ_CPIJ000670 antikoerper, Dhcr24 antikoerper

Hintergrund: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.,DHCR24,DCE,Nbla03646,SELADIN1,seladin-1,Cancer,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Lipids,DHCR24

Molekulargewicht: 54 kDa/60 kDa

Gen-ID: 1718

UniProt: Q15392