CYP3A5 Antikörper (AA 233-502)

Produktnummer ABIN6139354

Produktdetails anti-CYP3A5 Antikörper

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Bindungsspezifität: AA 233-502

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP3A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FEALNVSLFP KDTINFLSKS VNRMKKSRLN DKQKHRLDFL QLMIDSQNSK ETESHKALSD LELAAQSIIF IFAGYETTSS VLSFTLYELA THPDVQQKLQ KEIDAVLPNK APPTYDAVVQ MEYLDMVVNE TLRLFPVAIR LERTCKKDVE INGVFIPKGS MVVIPTYALH HDPKYWTEPE EFRPERFSKK KDSIDPYIYT PFGTGPRNCI GMRFALMNMK LALIRVLQNF SFKPCKETQI PLKLDTQGLL QPEKPIVLKV DSRDGTLSGE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 233-502 of human CYP3A5 (NP_000768.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP3A5

Target: CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))

Andere Bezeichnung: CYP3A5 (CYP3A5 Produkte)

Synonyme: CP35 antikoerper, CYPIIIA5 antikoerper, P450PCN3 antikoerper, PCN3 antikoerper, cytochrome P450 family 3 subfamily A member 5 antikoerper, CYP3A5 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.,CYP3A5,CP35,CYPIIIA5,P450PCN3,PCN3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP3A5

Molekulargewicht: 15 kDa/57 kDa

Gen-ID: 1577

UniProt: P20815

Pathways: Steroid Hormone Biosynthesis