CYP1B1 Antikörper (AA 244-543)

Produktnummer ABIN6139321

Produktdetails anti-CYP1B1 Antikörper

Target: CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))

Bindungsspezifität: AA 244-543

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MPWLQYFPNP VRTVFREFEQ LNRNFSNFIL DKFLRHCESL RPGAAPRDMM DAFILSAEKK AAGDSHGGGA RLDLENVPAT ITDIFGASQD TLSTALQWLL LLFTRYPDVQ TRVQAELDQV VGRDRLPCMG DQPNLPYVLA FLYEAMRFSS FVPVTIPHAT TANTSVLGYH IPKDTVVFVN QWSVNHDPLK WPNPENFDPA RFLDKDGLIN KDLTSRVMIF SVGKRRCIGE ELSKMQLFLF ISILAHQCDF RANPNEPAKM NFSYGLTIKP KSFKVNVTLR ESMELLDSAV QNLQAKETCQ

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human CYP1B1 (NP_000095.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP1B1

Target: CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))

Andere Bezeichnung: CYP1B1 (CYP1B1 Produkte)

Synonyme: CP1B antikoerper, CYPIB1 antikoerper, GLC3A antikoerper, P4501B1 antikoerper, P4501b1 antikoerper, CYP1B1 antikoerper, CYP1B antikoerper, zgc:136223 antikoerper, cytochrome P450 family 1 subfamily B member 1 antikoerper, cytochrome P450, family 1, subfamily b, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily B, polypeptide 1 antikoerper, cytochrome P450 1B1 antikoerper, CYP1B1 antikoerper, Cyp1b1 antikoerper, cyp1b1 antikoerper, LOC100719054 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.,CYP1B1,ASGD6,CP1B,CYPIB1,GLC3A,P4501B1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Drug metabolism,Neuroscience,Cardiovascular,Lipids,CYP1B1

Molekulargewicht: 60 kDa

Gen-ID: 1545

UniProt: Q16678

Pathways: Steroid Hormone Biosynthesis