CBFA2T2 Antikörper (AA 325-604)
-
- Target Alle CBFA2T2 Antikörper anzeigen
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
-
Bindungsspezifität
- AA 325-604
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CBFA2T2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- GLNGGYQDEL VDHRLTEREW ADEWKHLDHA LNCIMEMVEK TRRSMAVLRR CQESDREELN YWKRRYNENT ELRKTGTELV SRQHSPGSAD SLSNDSQREF NSRPGTGYVP VEFWKKTEEA VNKVKIQAMS EVQKAVAEAE QKAFEVIATE RARMEQTIAD VKRQAAEDAF LVINEQEEST ENCWNCGRKA SETCSGCNIA RYCGSFCQHK DWERHHRLCG QNLHGQSPHG QGRPLLPVGR GSSARSADCS VPSPALDKTS ATTSRSSTPA SVTAIDTNGL
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 325-604 of human CBFA2T2 (NP_005084.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CBFA2T2 Primärantikörper
-
-
- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- Kommentare
-
HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- Andere Bezeichnung
- CBFA2T2 (CBFA2T2 Produkte)
- Synonyme
- MTGR1 antikoerper, A430091M07 antikoerper, C330013D05Rik antikoerper, Cbfa2t2h antikoerper, EHT antikoerper, ZMYND3 antikoerper, p85 antikoerper, XETOR antikoerper, cbfa2t2-a antikoerper, CBFA2/RUNX1 translocation partner 2 antikoerper, core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) antikoerper, CBFA2/RUNX1 translocation partner 2 L homeolog antikoerper, Cbfa2t2 antikoerper, CBFA2T2 antikoerper, cbfa2t2.L antikoerper
- Hintergrund
- In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.,CBFA2T2,EHT,MTGR1,ZMYND3,p85,CBFA2T2
- Molekulargewicht
- 28 kDa/63 kDa/65 kDa/67 kDa
- Gen-ID
- 9139
- UniProt
- O43439
-