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ATM Antikörper (AA 1900-2000)

ATM Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6137281
  • Target Alle ATM Antikörper anzeigen
    ATM (Ataxia Telangiectasia Mutated (ATM))
    Bindungsspezifität
    • 33
    • 16
    • 15
    • 13
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1900-2000
    Reaktivität
    • 162
    • 84
    • 34
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 138
    • 24
    • 6
    • 2
    Kaninchen
    Klonalität
    • 132
    • 38
    Polyklonal
    Konjugat
    • 81
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser ATM Antikörper ist unkonjugiert
    Applikation
    • 73
    • 50
    • 39
    • 37
    • 28
    • 26
    • 22
    • 22
    • 19
    • 13
    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    CLDKKSQRTM LAVVDYMRRQ KRPSSGTIFN DAFWLDLNYL EVAKVAQSCA AHFTALLYAE IYADKKSMDD QEKRSLAFEE GSQSTTISSL SEKSKEETGI S
    Kreuzreaktivität
    Human
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human ATM (NP_000042.3).
    Isotyp
    IgG
    Top Product
    Discover our top product ATM Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:1000
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Peng, Qi, Miao, Ren: "1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase." in: Acta pharmacologica Sinica, Vol. 38, Issue 4, pp. 561-570, (2017) (PubMed).

  • Target
    ATM (Ataxia Telangiectasia Mutated (ATM))
    Andere Bezeichnung
    ATM (ATM Produkte)
    Synonyme
    ATM antikoerper, Atm antikoerper, CG6535 antikoerper, Dmel\\CG6535 antikoerper, Tefu antikoerper, atm antikoerper, atm/tefu antikoerper, dATM antikoerper, tef antikoerper, Xatm antikoerper, at1 antikoerper, atdc antikoerper, tel1 antikoerper, telo1 antikoerper, AT1 antikoerper, ATA antikoerper, ATC antikoerper, ATD antikoerper, ATDC antikoerper, ATE antikoerper, TEL1 antikoerper, TELO1 antikoerper, AI256621 antikoerper, C030026E19Rik antikoerper, telomere fusion antikoerper, ATM serine/threonine kinase L homeolog antikoerper, ATM serine/threonine kinase antikoerper, ataxia telangiectasia mutated antikoerper, ataxia telangiectasia mutated (atm) antikoerper, serine/threonine-protein kinase ATM antikoerper, tefu antikoerper, atm.L antikoerper, atm antikoerper, ATM antikoerper, EDI_100660 antikoerper, CpipJ_CPIJ001772 antikoerper, BDBG_08252 antikoerper, PAAG_02532 antikoerper, MCYG_05088 antikoerper, VDBG_06833 antikoerper, ACLA_015700 antikoerper, LOC5565620 antikoerper, MGYG_07634 antikoerper, PGTG_14279 antikoerper, Atm antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.,AT1,ATA,ATC,ATD,ATDC,ATE,TEL1,TELO1,ATM,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,DNA Damage & Repair,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cell Cycle,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Immunology & Inflammation,NF-kB Signaling Pathway,ATM
    Molekulargewicht
    350 kDa
    Gen-ID
    472
    UniProt
    Q13315
    Pathways
    p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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