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CD137 Antikörper (FITC)

TNFRSF9 Reaktivität: Human ELISA, FACS, Func Wirt: Maus Monoclonal 4B4-1 FITC
Produktnummer ABIN610408
  • Target Alle CD137 (TNFRSF9) Antikörper anzeigen
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    Reaktivität
    • 96
    • 42
    • 26
    • 8
    • 4
    • 1
    • 1
    Human
    Wirt
    • 45
    • 40
    • 12
    • 11
    • 5
    • 1
    Maus
    Klonalität
    • 62
    • 47
    • 3
    Monoklonal
    Konjugat
    • 60
    • 14
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD137 Antikörper ist konjugiert mit FITC
    Applikation
    • 72
    • 59
    • 53
    • 15
    • 14
    • 12
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Functional Studies (Func)
    Spezifität
    CD137 Molecule of about 35 kd from activated T cells.
    Aufreinigung
    Protein A purified
    Immunogen
    Ectodomain of recombinant human 4-1BB fusion protein.

    Type of Immunogen: Fusion protein
    Klon
    4B4-1
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF9 Primärantikörper
  • Applikationshinweise
    Approved: ELISA, Flo, Func

    Usage: Function: Blocks binding of CD137 huIg to Raji cells. Immobilized mAb induces TNF a production by monocytes. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze. Product is photosensitive and should be protected from light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C. Do not freeze. Protect from light.
  • Radoja, Saio, Schaer, Koneru, Vukmanovic, Frey: "CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 9, pp. 5042-51, (2001) (PubMed).

    Clark, Hynes: "Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14814-8, (1996) (PubMed).

    Cobb, Goldsmith: "How MAP kinases are regulated." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14843-6, (1995) (PubMed).

    Boulton, Cobb: "Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies." in: Cell regulation, Vol. 2, Issue 5, pp. 357-71, (1991) (PubMed).

  • Target
    CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
    Andere Bezeichnung
    TNFRSF9 / 4-1BB / CD137 (TNFRSF9 Produkte)
    Synonyme
    TNFRSF9 antikoerper, zgc:136557 antikoerper, 4-1BB antikoerper, CD137 antikoerper, CDw137 antikoerper, ILA antikoerper, A930040I11Rik antikoerper, AA408498 antikoerper, AI325004 antikoerper, Cd137 antikoerper, Ly63 antikoerper, tumor necrosis factor receptor superfamily member 9 antikoerper, TNF receptor superfamily member 9 antikoerper, tumor necrosis factor receptor superfamily, member 9a antikoerper, tumor necrosis factor receptor superfamily, member 9 antikoerper, TNFRSF9 antikoerper, tnfrsf9a antikoerper, Tnfrsf9 antikoerper
    Hintergrund
    Name/Gene ID: TNFRSF9
    Family: TNF Receptor

    Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137
    Gen-ID
    3604
    UniProt
    Q07011
    Pathways
    Cancer Immune Checkpoints
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