PTPN2 Antikörper

Produktnummer ABIN5967602

Produktdetails anti-PTPN2 Antikörper

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PTPN2 (NP_536348.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPN2

Target: PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))

Andere Bezeichnung: PTPN2 (PTPN2 Produkte)

Synonyme: PTN2 antikoerper, PTPT antikoerper, TC-PTP antikoerper, TCELLPTP antikoerper, TCPTP antikoerper, AI325124 antikoerper, Ptpt antikoerper, PTP-1B antikoerper, cb806 antikoerper, ptpn2 antikoerper, ptpn2l antikoerper, wu:fc10h07 antikoerper, zgc:55339 antikoerper, zgc:76973 antikoerper, hm:zeh1546 antikoerper, zgc:63623 antikoerper, ptn2 antikoerper, ptpt antikoerper, tc-ptp antikoerper, tcellptp antikoerper, tcptp antikoerper, protein tyrosine phosphatase, non-receptor type 2 antikoerper, protein tyrosine phosphatase, non-receptor type 2 S homeolog antikoerper, protein tyrosine phosphatase, non-receptor type 2, b antikoerper, protein tyrosine phosphatase, non-receptor type 2, a antikoerper, protein tyrosine phosphatase, non-receptor type 2 L homeolog antikoerper, PTPN2 antikoerper, Ptpn2 antikoerper, ptpn2.S antikoerper, ptpn2b antikoerper, ptpn2a antikoerper, ptpn2.L antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Molekulargewicht:

Observed_MW: 45kDa

Calculated_MW: 40kDa/45kDa/48kDa

Gen-ID: 5771

UniProt: P17706

Pathways: EGFR Signaling Pathway, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling