PPP2R4 Antikörper

Produktnummer ABIN5967578

Produktdetails anti-PPP2R4 Antikörper

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PPP2R4 (NP_821067.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Andere Bezeichnung: PPP2R4 (PPP2R4 Produkte)

Synonyme: PP2A antikoerper, PR53 antikoerper, PTPA antikoerper, 2610042B21Rik antikoerper, C77440 antikoerper, N28142 antikoerper, PTPRA antikoerper, Ppp2r4 antikoerper, fc23d07 antikoerper, ppp2r4 antikoerper, wu:fc23d07 antikoerper, zgc:92766 antikoerper, pp2a antikoerper, ppp2r4.L antikoerper, pr53 antikoerper, ptpa antikoerper, protein phosphatase 2 phosphatase activator antikoerper, protein phosphatase 2 protein activator antikoerper, protein phosphatase 2 phosphatase activator L homeolog antikoerper, PTPA antikoerper, Ptpa antikoerper, ptpa antikoerper, ptpa.L antikoerper

Hintergrund: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Calculated_MW: 31kDa/33kDa/36kDa/40kDa

Gen-ID: 5524

UniProt: Q15257

Pathways: PI3K-Akt Signalweg, M Phase, Hepatitis C, Toll-Like Receptors Cascades