POT1 Antikörper

Produktnummer ABIN5967576

Produktdetails anti-POT1 Antikörper

Target: POT1 (Protection of Telomeres 1 (POT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human POT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Andere Bezeichnung: POT1 (POT1 Produkte)

Synonyme: HPOT1 antikoerper, POT1 antikoerper, DKFZp469P1825 antikoerper, pot1 antikoerper, 1500031H18Rik antikoerper, AI851169 antikoerper, Pot1 antikoerper, Pot1a antikoerper, protection of telomeres 1 antikoerper, protection of telomeres 1 L homeolog antikoerper, protection of telomeres 1A antikoerper, POT1 antikoerper, pot1.L antikoerper, Pot1a antikoerper, Pot1 antikoerper

Hintergrund:

Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1

Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Molekulargewicht:

Observed_MW: 75kDa

Calculated_MW: 60kDa/71kDa

Gen-ID: 25913

UniProt: Q9NUX5

Pathways: Zellzyklus, Telomere Maintenance