PSMC5 Antikörper

Produktnummer ABIN5967123

Produktdetails anti-PSMC5 Antikörper

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PSMC5 (NP_002796.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Andere Bezeichnung: PSMC5 (PSMC5 Produkte)

Synonyme: mSUG1 antikoerper, S8 antikoerper, SUG-1 antikoerper, SUG1 antikoerper, TBP10 antikoerper, TRIP1 antikoerper, p45 antikoerper, p45/SUG antikoerper, wu:fa14g03 antikoerper, wu:fb23a11 antikoerper, zgc:92464 antikoerper, sug-1 antikoerper, sug1 antikoerper, tbp10 antikoerper, Sug1 antikoerper, PSMC5 antikoerper, xsug1 antikoerper, protease (prosome, macropain) 26S subunit, ATPase 5 antikoerper, proteasome 26S subunit, ATPase 5 antikoerper, proteasome 26S subunit, ATPase 5 L homeolog antikoerper, proteasome 26S subunit, ATPase 5 S homeolog antikoerper, Psmc5 antikoerper, PSMC5 antikoerper, psmc5 antikoerper, psmc5.L antikoerper, psmc5.S antikoerper

Hintergrund: PSMC5,S8,SUG-1,SUG1,TBP10,TRIP1,p45,p45/SUG,ATPase 5,The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 46kDa

Calculated_MW: 44kDa/45kDa

Gen-ID: 5705

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway