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GCK Antikörper

GCK Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5966837
  • Target Alle GCK Antikörper anzeigen
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Reaktivität
    • 70
    • 31
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 66
    • 8
    Kaninchen
    Klonalität
    • 69
    • 5
    Polyklonal
    Konjugat
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GCK Antikörper ist unkonjugiert
    Applikation
    • 58
    • 36
    • 34
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human GCK
    Isotyp
    IgG
    Top Product
    Discover our top product GCK Primärantikörper
  • Applikationshinweise
    IF 1:20 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Andere Bezeichnung
    GCK (GCK Produkte)
    Synonyme
    FGQTL3 antikoerper, GK antikoerper, GLK antikoerper, HHF3 antikoerper, HK4 antikoerper, HKIV antikoerper, HXKP antikoerper, LGLK antikoerper, MODY2 antikoerper, Gk antikoerper, Gls006 antikoerper, GCK antikoerper, BA4487 antikoerper, glk antikoerper, hk4 antikoerper, hhf3 antikoerper, hkiv antikoerper, hxkp antikoerper, gck-A antikoerper, mody2 antikoerper, glucokinase antikoerper, GLUKA antikoerper, RNGK2 antikoerper, glucokinase antikoerper, glucokinase (hexokinase 4) L homeolog antikoerper, glucokinase (hexokinase 4) antikoerper, GCK antikoerper, Gck antikoerper, glcK antikoerper, Bphyt_1025 antikoerper, Halhy_6548 antikoerper, gk antikoerper, gck.L antikoerper, gck antikoerper
    Hintergrund

    Synonyms: ATP:D-hexose 6-phosphotransferase,FGQTL3,GCK,GK,GLK,Glucokinase,Hexokinase D pancreatic isozyme,Hexokinase type IV,Hexokinase-4,Hexokinase-D,HHF3,HK IV,HK4,HKIV,HXK4,HXKP,LGLK,MODY2

    Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

    Molekulargewicht

    Calculated_MW: 52kDa

    Gen-ID
    2645
    UniProt
    P35557
    Pathways
    MAPK Signalweg, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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