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IDE Antikörper

IDE Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5965765
  • Target Alle IDE Antikörper anzeigen
    IDE (Insulin-Degrading Enzyme (IDE))
    Reaktivität
    • 63
    • 27
    • 24
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 52
    • 10
    • 4
    Kaninchen
    Klonalität
    • 56
    • 10
    Polyklonal
    Konjugat
    • 37
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IDE Antikörper ist unkonjugiert
    Applikation
    • 59
    • 27
    • 19
    • 14
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human IDE
    Isotyp
    IgG
    Top Product
    Discover our top product IDE Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000 IF 1:10 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IDE (Insulin-Degrading Enzyme (IDE))
    Andere Bezeichnung
    IDE (IDE Produkte)
    Synonyme
    zgc:162603 antikoerper, IDE antikoerper, 1300012G03Rik antikoerper, 4833415K22Rik antikoerper, AA675336 antikoerper, AI507533 antikoerper, INSDEGM antikoerper, INSULYSIN antikoerper, insulin degrading enzyme antikoerper, insulin-degrading enzyme antikoerper, metallopeptidase antikoerper, IDE antikoerper, ide antikoerper, LOC591315 antikoerper, CC1G_01115 antikoerper, Bm1_26615 antikoerper, PTRG_10875 antikoerper, SJAG_01430 antikoerper, EBI_21700 antikoerper, VDBG_06702 antikoerper, LOAG_08082 antikoerper, PGTG_04982 antikoerper, Tsp_00424 antikoerper, Ide antikoerper
    Hintergrund

    Synonyms: Abeta-degrading protease,FLJ35968,Ide,IDE,Insulin protease,Insulin-degrading enzyme,Insulinase,Insulysin,OTTHUMP00000020097

    Background: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

    Molekulargewicht

    Observed_MW: 118kDa

    Calculated_MW: 54kDa/117kDa

    Gen-ID
    3416
    UniProt
    P14735
    Pathways
    SARS-CoV-2 Protein Interaktom
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