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NSD1 Antikörper

NSD1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5963837
  • Target Alle NSD1 Antikörper anzeigen
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    Reaktivität
    • 27
    • 17
    • 15
    • 1
    Human, Maus
    Wirt
    • 20
    • 8
    Kaninchen
    Klonalität
    • 21
    • 7
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NSD1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 9
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human NSD1
    Isotyp
    IgG
    Top Product
    Discover our top product NSD1 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    Andere Bezeichnung
    NSD1 (NSD1 Produkte)
    Synonyme
    NSD1 antikoerper, sto antikoerper, kmt3b antikoerper, sotos antikoerper, ara267 antikoerper, ARA267 antikoerper, KMT3B antikoerper, SOTOS antikoerper, SOTOS1 antikoerper, STO antikoerper, AI528500 antikoerper, nuclear receptor binding SET domain protein 1 antikoerper, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antikoerper, nuclear receptor-binding SET-domain protein 1 antikoerper, NSD1 antikoerper, nsd1 antikoerper, Nsd1 antikoerper, LOC540197 antikoerper
    Hintergrund

    Synonyms: Nuclear Receptor Binding SET Domain Protein 1,Nuclear Receptor-Binding SET Domain-Containing Protein 1,Androgen Receptor-Associated Protein Of 267 KDa,Androgen Receptor Coactivator 267 KDa Protein,NR-Binding SET Domain-Containing Protein,Lysine N-Methyltransferase 3B,H3-K36-HMTase,H4-K20-HMTase,EC 2.1.1.43.

    Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Molekulargewicht

    Observed_MW: 297kDa

    Calculated_MW: 267kDa/284kDa/296kDa

    Gen-ID
    64324
    UniProt
    Q96L73
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