CD161 Antikörper (APC)

Produktnummer ABIN5711621

Produktdetails anti-CD161 Antikörper (APC)

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD161 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody HP-3G10 recognizes an extracellular epitope of CD161, a type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer.

Kreuzreaktivität (Details): Human, Non-Human Primates

Aufreinigung: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: human NK cells

Klon: HP-3G10

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Kommentare:

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CD161

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Andere Bezeichnung: CD161 (KLRB1 Produkte)

Synonyme: NKR-P1 antikoerper, KLRB1 antikoerper, 4930431A04Rik antikoerper, Gm4696 antikoerper, Klrb1g antikoerper, Klrb6 antikoerper, Ly-55 antikoerper, Ly55 antikoerper, NKR-P1G antikoerper, Nkrp-1e antikoerper, Nkrp1g antikoerper, CD161 antikoerper, CLEC5B antikoerper, NKR antikoerper, NKR-P1A antikoerper, NKRP1A antikoerper, hNKR-P1A antikoerper, Klrb1d antikoerper, Klrb1f antikoerper, Nkr-p1e antikoerper, killer cell lectin like receptor B1 antikoerper, killer cell lectin-like receptor subfamily B member 1 antikoerper, killer cell lectin-like receptor subfamily B, member 1 antikoerper, KLRB1 antikoerper, Klrb1 antikoerper

Hintergrund: Killer cell lectin like receptor B1,CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.,NKRP1A, KLRB1, CLEC5B

Gen-ID: 3820

UniProt: Q12918