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CHM Antikörper

CHM Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5708426
  • Target Alle CHM Antikörper anzeigen
    CHM (Choroideremia (Rab Escort Protein 1) (CHM))
    Reaktivität
    • 30
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    Human
    Wirt
    • 25
    • 5
    Kaninchen
    Klonalität
    • 29
    • 1
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHM Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A recombinant human protein corresponding to amino acids A193-Q380 was used as the immunogen for the CHM antibody.
    Isotyp
    IgG
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    Discover our top product CHM Primärantikörper
  • Applikationshinweise
    Optimal dilution of the CHM antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the CHM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    CHM (Choroideremia (Rab Escort Protein 1) (CHM))
    Andere Bezeichnung
    CHM / Choroideremia protein (CHM Produkte)
    Synonyme
    CHM antikoerper, REP1 antikoerper, DXS540 antikoerper, GGTA antikoerper, HSD-32 antikoerper, REP-1 antikoerper, TCD antikoerper, DKFZp459K2154 antikoerper, tcd antikoerper, ggta antikoerper, rep-1 antikoerper, dxs540 antikoerper, hsd-32 antikoerper, MGC68578 antikoerper, Rep-1 antikoerper, chm antikoerper, chm-a antikoerper, chm-b antikoerper, chml antikoerper, CHM, Rab escort protein 1 antikoerper, choroideremia (Rab escort protein 1) antikoerper, choroideremia (Rab escort protein 1) L homeolog antikoerper, choroidermia (RAB escort protein 1) antikoerper, choroideremia (Rab escort protein 1) S homeolog antikoerper, CHM antikoerper, chm antikoerper, chm.L antikoerper, Chm antikoerper, chm.S antikoerper
    Hintergrund
    Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
    UniProt
    P24386
    Pathways
    Sensory Perception of Sound
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