CHM Antikörper
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- Target Alle CHM Antikörper anzeigen
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A recombinant human protein corresponding to amino acids A193-Q380 was used as the immunogen for the CHM antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CHM Primärantikörper
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- Applikationshinweise
- Optimal dilution of the CHM antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the CHM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- Andere Bezeichnung
- CHM / Choroideremia protein (CHM Produkte)
- Synonyme
- CHM antikoerper, REP1 antikoerper, DXS540 antikoerper, GGTA antikoerper, HSD-32 antikoerper, REP-1 antikoerper, TCD antikoerper, DKFZp459K2154 antikoerper, tcd antikoerper, ggta antikoerper, rep-1 antikoerper, dxs540 antikoerper, hsd-32 antikoerper, MGC68578 antikoerper, Rep-1 antikoerper, chm antikoerper, chm-a antikoerper, chm-b antikoerper, chml antikoerper, CHM, Rab escort protein 1 antikoerper, choroideremia (Rab escort protein 1) antikoerper, choroideremia (Rab escort protein 1) L homeolog antikoerper, choroidermia (RAB escort protein 1) antikoerper, choroideremia (Rab escort protein 1) S homeolog antikoerper, CHM antikoerper, chm antikoerper, chm.L antikoerper, Chm antikoerper, chm.S antikoerper
- Hintergrund
- Rab escort protein 1 (REP1) also known as rab proteins geranylgeranyltransferase component A 1 is an enzyme that in humans is encoded by the CHM gene. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.
- UniProt
- P24386
- Pathways
- Sensory Perception of Sound
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