DYNLT1 Antikörper

Produktnummer ABIN5708410

Produktdetails anti-DYNLT1 Antikörper

Target: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNLT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids M1-A80 was used as the immunogen for the DYNLT1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DYNLT1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the DYNLT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu DYNLT1

Target: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Andere Bezeichnung: DYNLT1 (DYNLT1 Produkte)

Synonyme: cw-1 antikoerper, tctel1 antikoerper, dynlt1a antikoerper, tctex-1 antikoerper, MGC85297 antikoerper, tctex1 antikoerper, Ci-LC3 antikoerper, CW-1 antikoerper, TCTEL1 antikoerper, AGS2 antikoerper, Tctex1 antikoerper, dynein light chain Tctex-type 1 L homeolog antikoerper, dynein light chain Tctex-type 1 antikoerper, dynein, light chain, Tctex-type 1 antikoerper, dynlt1.L antikoerper, DYNLT1 antikoerper, dynlt1 antikoerper, Dynlt1 antikoerper

Hintergrund: Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P63172

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling