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Betacellulin Antikörper

BTC Reaktivität: Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5708196
  • Target Alle Betacellulin (BTC) Antikörper anzeigen
    Betacellulin (BTC)
    Reaktivität
    • 46
    • 33
    • 12
    • 2
    • 1
    Maus, Ratte
    Wirt
    • 62
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 65
    • 5
    Polyklonal
    Konjugat
    • 33
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Betacellulin Antikörper ist unkonjugiert
    Applikation
    • 62
    • 20
    • 16
    • 13
    • 13
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A rat partial recombinant protein corresponding to amino acids D32-A177 was used as the immunogen for the Betacellulin antibody.
    Isotyp
    IgG
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  • Applikationshinweise
    Optimal dilution of the Betacellulin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant rat protein) (BSA-free format available)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the Betacellulin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Betacellulin (BTC)
    Andere Bezeichnung
    Betacellulin / BTC (BTC Produkte)
    Synonyme
    BTC antikoerper, LOC100228121 antikoerper, probetacellulin antikoerper, Bcn antikoerper, betacellulin antikoerper, betacellulin, epidermal growth factor family member antikoerper, BTC antikoerper, LOC100228121 antikoerper, Btc antikoerper
    Hintergrund
    Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
    UniProt
    Q9JJM4
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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