MYOD1 Antikörper

Produktnummer ABIN5707998

Produktdetails anti-MYOD1 Antikörper

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MYOD1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for this recombinant MyoD antibody.

Klon: MYOD1-2075R

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the recombinant MyoD antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant MyoD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Andere Bezeichnung: MyoD1 (MYOD1 Produkte)

Synonyme: MYF3 antikoerper, MYOD antikoerper, PUM antikoerper, bHLHc1 antikoerper, MyoD antikoerper, XMyoD antikoerper, XtmyoD antikoerper, mf25 antikoerper, myf3 antikoerper, pum antikoerper, MUF3 antikoerper, AI503393 antikoerper, Myod-1 antikoerper, etID309723.25 antikoerper, myod antikoerper, wu:fb57a01 antikoerper, zgc:136744 antikoerper, MYOD1 antikoerper, myod1 antikoerper, mf1 antikoerper, myod1-a antikoerper, myod1-b antikoerper, myogenic differentiation 1 antikoerper, MYOD protein antikoerper, myogenic factor MyoD1 antikoerper, myogenic differentiation 1 S homeolog antikoerper, myogenic differentiation 1 L homeolog antikoerper, MYOD1 antikoerper, myod1 antikoerper, Myod1 antikoerper, myod antikoerper, myod1.S antikoerper, myod1.L antikoerper

Hintergrund: MyoD, or MYOD1, is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. The effect of MyoD on satellite cells is dose-dependent, high MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. This is likely due to functional redundancy from Myf5 and/or Mrf4. Nevertheless, the combination of MyoD and Myf5 is vital to the success of myogenesis. [Wiki]

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development