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POLR3G Antikörper

POLR3G Reaktivität: Human WB, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5705942
  • Target Alle POLR3G Antikörper anzeigen
    POLR3G (Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))
    Reaktivität
    • 29
    • 3
    • 1
    • 1
    Human
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLR3G Antikörper ist unkonjugiert
    Applikation
    • 22
    • 18
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Immunogen
    polymerase (RNA) III (DNA directed) polypeptide G (32kD)
    Isotyp
    IgG
    Top Product
    Discover our top product POLR3G Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    POLR3G (Polymerase (RNA) III (DNA Directed) Polypeptide G (32kD) (POLR3G))
    Andere Bezeichnung
    POLR3G (POLR3G Produkte)
    Synonyme
    2310047G20Rik antikoerper, AV275904 antikoerper, RPC32 antikoerper, RPC7 antikoerper, polymerase (RNA) III (DNA directed) polypeptide G antikoerper, RNA polymerase III subunit G antikoerper, Polr3g antikoerper, POLR3G antikoerper
    Hintergrund
    Synonyms: Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
    Gen-ID
    10622
    UniProt
    O15318
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