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ALKBH7 Antikörper

ALKBH7 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5705608
  • Target Alle ALKBH7 Antikörper anzeigen
    ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 10
    Kaninchen
    Klonalität
    • 10
    Polyklonal
    Konjugat
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALKBH7 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    alkB, alkylation repair homolog 7 (E. coli)
    Isotyp
    IgG
    Top Product
    Discover our top product ALKBH7 Primärantikörper
  • Applikationshinweise
    WB :1:200-1:2000,IHC:1:20-1:200
    Kommentare

    human testis tissue were subjected to SDS PAGE followed by western blot with FNab00315(ALKBH7 antibody) at dilution of 1:500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))
    Andere Bezeichnung
    ALKBH7 (ALKBH7 Produkte)
    Synonyme
    ABH7 antikoerper, SPATA11 antikoerper, UNQ6002 antikoerper, 2310045B01Rik antikoerper, 2510008E23Rik antikoerper, Abh7 antikoerper, Spata11 antikoerper, alkB homolog 7 antikoerper, Alkbh7 antikoerper, ALKBH7 antikoerper
    Hintergrund
    Synonyms:ABH7, ALKBH7, SPATA11, UNQ6002 Background:May function as protein hydroxylase, can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).
    Molekulargewicht
    25kDa
    Gen-ID
    84266
    UniProt
    Q9BT30
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