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CCDC22 Antikörper

CCDC22 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5705501
  • Target Alle CCDC22 Antikörper anzeigen
    CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC22 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 16
    • 15
    • 13
    • 13
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Immunogen
    coiled-coil domain containing 22
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC22 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))
    Andere Bezeichnung
    CCDC22 (CCDC22 Produkte)
    Synonyme
    CXorf37 antikoerper, AI481216 antikoerper, DXImx40e antikoerper, Ppp1r3f antikoerper, Sfc22 antikoerper, RGD1560910 antikoerper, zgc:114058 antikoerper, coiled-coil domain containing 22 antikoerper, CCDC22 antikoerper, Ccdc22 antikoerper, ccdc22 antikoerper
    Hintergrund
    Synonyms:CXorf37 Background:Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation, the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via assocation with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10(PubMed:23563313). Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery, the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes(PubMed:25355947).
    Molekulargewicht
    71 kDa
    Gen-ID
    28952
    UniProt
    O60826
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