MSL1 Antikörper

Produktnummer ABIN5705283

Produktdetails anti-MSL1 Antikörper

Target: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: male-specific lethal 1 homolog (Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MSL1

Target: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Andere Bezeichnung: MSL1 (MSL1 Produkte)

Synonyme: MSL-1 antikoerper, hMSL1 antikoerper, 2810017F12Rik antikoerper, 4121402D02Rik antikoerper, 4930463F05Rik antikoerper, AA682082 antikoerper, Msl-1 antikoerper, male specific lethal 1 homolog antikoerper, male-specific lethal 1 homolog (Drosophila) antikoerper, MSL1 antikoerper, Msl1 antikoerper

Hintergrund: Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.

Molekulargewicht: 67 kDa

Gen-ID: 339287

UniProt: Q68DK7