THOC7 Antikörper

Produktnummer ABIN5705193

Produktdetails anti-THOC7 Antikörper

Target: THOC7 (THO Complex 7 (THOC7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THOC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: THO complex 7 homolog (Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08670(THOC7 antibody) at dilution of 1:800

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu THOC7

Target: THOC7 (THO Complex 7 (THOC7))

Andere Bezeichnung: THOC7 (THOC7 Produkte)

Synonyme: RGD1305475 antikoerper, NIF3L1BP1 antikoerper, fSAP24 antikoerper, 1500006O09Rik antikoerper, 9230101K24Rik antikoerper, Nif3l1bp1 antikoerper, THO complex 7 antikoerper, Thoc7 antikoerper, THOC7 antikoerper

Hintergrund: Synonyms:NIF3L1BP1 Background:Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production.

Gen-ID: 80145

UniProt: Q6I9Y2