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MMS19 Antikörper

MMS19 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN5704840
  • Target Alle MMS19 Antikörper anzeigen
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 26
    • 4
    Maus
    Klonalität
    • 28
    • 2
    Monoklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MMS19 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 13
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    Immunogen
    MMS19 nucleotide excision repair homolog (S. cerevisiae)
    Isotyp
    IgG2a
    Top Product
    Discover our top product MMS19 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Andere Bezeichnung
    MMS19 (MMS19 Produkte)
    Synonyme
    MET18 antikoerper, MMS19L antikoerper, hMMS19 antikoerper, 2410001K24Rik antikoerper, 2610042O15Rik antikoerper, AI316855 antikoerper, C79368 antikoerper, C86341 antikoerper, Mms19l antikoerper, mms19 antikoerper, mms19l antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component antikoerper, MMS19 (MET18 S. cerevisiae) antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antikoerper, MMS19 antikoerper, Mms19 antikoerper, mms19.L antikoerper
    Hintergrund
    Synonyms:MMS19L Background:Key component of the cytosolic iron-sulfur protein assembly(CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair(NER) and RNA polymerase II(POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor(ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
    Molekulargewicht
    103 kDa
    Gen-ID
    64210
    UniProt
    Q96T76
    Pathways
    Nuclear Hormone Receptor Binding
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