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NUMBL Antikörper

NUMBL Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN5704050
  • Target Alle NUMBL Antikörper anzeigen
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Reaktivität
    • 47
    • 9
    • 9
    • 1
    Human
    Wirt
    • 45
    • 1
    • 1
    Maus
    Klonalität
    • 46
    • 1
    Monoklonal
    Konjugat
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NUMBL Antikörper ist unkonjugiert
    Applikation
    • 32
    • 22
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    numb homolog (Drosophila)-like
    Isotyp
    IgG2a
    Top Product
    Discover our top product NUMBL Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    L02 cells were subjected to SDS PAGE followed by western blot with FNab05918( NUMBLIKE Antibody) at dilution of 1:1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Andere Bezeichnung
    NUMBL (NUMBL Produkte)
    Synonyme
    nbl antikoerper, numb antikoerper, cag3a antikoerper, ctg3a antikoerper, numbr antikoerper, numb-r antikoerper, tnrc23 antikoerper, numblike antikoerper, CAG3A antikoerper, CTG3a antikoerper, NBL antikoerper, NUMB-R antikoerper, NUMBLIKE antikoerper, NUMBR antikoerper, TNRC23 antikoerper, NUMB like, endocytic adaptor protein antikoerper, numb homolog-like L homeolog antikoerper, NUMB-like, endocytic adaptor protein antikoerper, numb-like antikoerper, NUMBL antikoerper, numbl.L antikoerper, Numbl antikoerper
    Hintergrund
    Synonyms: Background:Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells(RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone(SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
    Molekulargewicht
    65-70 kDa
    Gen-ID
    9253
    UniProt
    Q9Y6R0
    Pathways
    Cell-Cell Junction Organization
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