GEMIN8 Antikörper
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- Target Alle GEMIN8 Antikörper anzeigen
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GEMIN8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- gem (nuclear organelle) associated protein 8
- Isotyp
- IgG
- Top Product
- Discover our top product GEMIN8 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab03423(GEMIN8 antibody) at dilution of 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
- Andere Bezeichnung
- GEMIN8 (GEMIN8 Produkte)
- Synonyme
- FAM51A1 antikoerper, B130034M20Rik antikoerper, B930082C09Rik antikoerper, BC023488 antikoerper, gemin-8 antikoerper, gem nuclear organelle associated protein 8 antikoerper, gemin8 antikoerper, GEMIN8 antikoerper, Gemin8 antikoerper
- Hintergrund
- Synonyms:FAM51A1 Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
- Molekulargewicht
- 32 kDa
- Gen-ID
- 54960
- UniProt
- Q9NWZ8
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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