GEMIN6 Antikörper

Produktnummer ABIN5703359

Produktdetails anti-GEMIN6 Antikörper

Target: GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEMIN6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: gem (nuclear organelle) associated protein 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GEMIN6

Target: GEMIN6 (Gem (Nuclear Organelle) Associated Protein 6 (GEMIN6))

Andere Bezeichnung: GEMIN6 (GEMIN6 Produkte)

Synonyme: 2610019B15Rik antikoerper, 2810470M17Rik antikoerper, gemin6 antikoerper, gem nuclear organelle associated protein 6 antikoerper, gem (nuclear organelle) associated protein 6 antikoerper, gem nuclear organelle associated protein 6 S homeolog antikoerper, GEMIN6 antikoerper, Gemin6 antikoerper, gemin6.S antikoerper

Hintergrund: Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Molekulargewicht: 19 kDa

Gen-ID: 79833

UniProt: Q8WXD5

Pathways: Ribonucleoprotein Complex Subunit Organization